WebJan 1, 2024 · In fully adjusted analyses, longer duration of statin use was associated with higher risk of colon cancer (hazard ratios, the 95% confidence interval was 1.09, 0.95-1.25 for 1-5 years; 1.16, 0.99-1.36 for 6-10 years; 1.08, 0.81-1.44 for 11-15 years; 1.85, 1.30-2.61 for >15 years; vs never users, P = 0.004 for trend) rather than rectal cancer. WebOct 1, 2024 · The ACC/AHA 2024 cholesterol guidelines state that in adults older than 75 years with diabetes mellitus, it may be reasonable to initiate statin therapy after a clinician–patient discussion of potential benefits and risks for prevention of ASCVD events.
The status of statins - Harvard Health
WebIt found that statins doubled the risk of developing diabetes, with the risk greatest among those taking statins for two years or longer. It found no differences by statin class or dose. “If somebody needs a statin, it is always a discussion with the patient. You’ve got to talk with patients because there is so much out there, especially on ... WebNov 17, 2024 · Severe muscle aching throughout the entire body Muscle weakness Dark or cola-colored urine The higher the dose of statins, the higher the risk of rhabdomyolysis becomes. The risk also increases if certain drugs — including cyclosporine (Sandimmune) and gemfibrozil (Lopid) — are taken in combination with statins. the pearse
Statin Side Effects: Are Statins Bad For You? - Healthline
WebDec 19, 2024 · Researchers who studied 500,000 residents of Denmark, about 9 percent of that country’s population, found that people who took statins were more likely to develop polyneuropathy. 11 Taking statins for … WebIn summary, a long-term benefit approach to statin eligibility using a 30-year ARR greater than or equal to 15% identifies approximately 17.5% of individuals as having a high degree … WebApr 7, 2024 · Patients with medium-term or long-term use of statins without discontinuation are at a lower risk of gallstone disease or cholecystectomy. ... Further subgroup analysis showed that short-term users, medium-term users, and long-term users were associated with a significantly higher risk (OR, 1.18; 95% CI [1.11-1.25]), comparable risk (OR, 0.93 ... siamang location