WebNov 13, 2024 · Mps1/TTK plays an important role in development of many tumors. The purpose of the present study was designed to investigate the role of TTK in colon cancer. We analyzed TTK and colon cancer in the GEO database, colon cancer tissues and normal tissues were collected to verify the results by immunohistochemistry. We detected the … WebFeb 25, 2024 · Cancer-testis antigens (CTAs) are often expressed in tumor and testicular tissues but not in other normal tissues. To date, there has been no comprehensive study of the expression and clinical significance of CTA genes associated with endometrial cancer (EC) development. Additionally, the clinical relevance, biological role, and molecular …
Genetic and pharmacological inhibition of TTK impairs pancreatic …
WebApr 5, 2024 · The list of identified TTK phosphorylation substrates remain sparse and the key substrates for TTK-dependent cancer growth remain unestablished [34–37]. The … WebOct 2, 2024 · Drug resistance and recurrence are main contributors to the poor prognosis of ovarian cancer. Cisplatin is a platinum compound which is widely used in the treatment of … how to share twitter
TTK is over-expressed in human endometrial cancer. - ResearchGate
WebApr 23, 2024 · Besides, the TTK expression is significantly increased in liver cancer [8,9]. Moreover, TTK was reported to promote cell proliferation and migration in liver cancer [10]. These results suggested that TTK may serve as a potential target in liver cancer therapy. TTK inhibitors effectively and selectively inhibit Mps1, and some of them are applied ... WebSep 12, 2024 · Increase in TTK expression and its correlation with higher tumor grade, triple negative status, and worse overall survival in breast cancer.a–d Box plots of TTK gene … WebOct 1, 2015 · Indeed, TTK is one of the genes included in the molecular signature of chromosome instability in human cancer—CIN70 [21]. This suggests that TTK inhibitors could specifically hamper cells that express high levels of TTK, and as a consequence, increase CIN and reduce cell viability. how to share twitch link